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PACAP-38 (31-38), human, mouse, rat

CAS No. 138764-85-9

PACAP-38 (31-38), human, mouse, rat( —— )

Catalog No. M30317 CAS No. 138764-85-9

PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PACAP-38 (31-38), human, mouse, rat
  • Note
    Research use only, not for human use.
  • Brief Description
    PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.
  • Description
    PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.
  • In Vitro
    Cell Viability Assay Cell Line:NCI-H838 cells Concentration:10 nM Incubation Time:48 hours Result:Increased the number of NCI-H838 cells by 72%.Western Blot Analysis Cell Line:100 nM Concentration:100 nM Incubation Time:2 minutes Result:Increased tyrosine phosphorylation of the EGFR, HER2, and ERK by 377, 299 and 216%, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    138764-85-9
  • Formula Weight
    1062.27
  • Molecular Formula
    C47H83N17O11
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (94.14 mM)
  • SMILES
    ——
  • Chemical Name
    Sequence:{Tyr}{Lys}{Gln}{Arg}{Val}{Lys}{Asn}{Lys}-NH2

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16.
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